CyanthOx™ may be 5 times more effective than bilberry anthocyanins extract
Design: Randomised, controlled trial was conducted in 40 healthy rabbits weighing from 2.5 to 3.0kg. The rabbits were exposed to light at 18,000lx for 2 hours.
Method and Material: Oral intake of 500mg 41.0% bilberry anthocyanins (BAE) /kg/day for 14 days before exposure and 7 days after exposure.
Result: 500mg 41% bilberry anthocyanins shows similar effects as 100mg 38.9% sea buckthorn proanthocyanidins.
Same level of reduction in Outer Nuclear Layer (ONL) thickness
9% more Improvement in photopic electroretinogram functions
Similar Improvement in scotopic and max electroretinogram functions
ONL Comparison
Photopic Electroretinogram
Conclusion: Sea buckthorn proanthocyanidins is 5.3 times more potent than bilberry anthocyanin.
(Wang et al., 2015)
Omegia® may improve dry eyes*
Design: Randomized, double-blinded, placebo-controlled, cross-over trial was conducted in 100 women of 20 - 75 years old
Dosage: Oral intake of 4 x 500mg sea buckthorn oil or placebo (Fractionated coconut and palm oil) per day for 3 months
Result: Significant improvement for eye health:
18% less subjects felt dryness in eyes compared with the placebo group
17% less subjects felt burning in eyes compared with the placebo group
Eye Dryness
Eye Burning
(Larmo et al., 2010)
Reference
Wang, Y., Zhao, L., Huo, Y., Zhou, F., Wu, W., Lu, F., Yang, X., Guo, X., Chen, P., Deng, Q. and Ji, B. (2016). Protective Effect of Proanthocyanidins from Sea Buckthorn (Hippophae Rhamnoides L.) Seed against Visible Light-Induced Retinal Degeneration in Vivo. Nutrients, [online] 8(5), p.245. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882658/.
Wang, Y., Zhao, L., Lu, F., Yang, X., Deng, Q., Ji, B. and Huang, F. (2015). Retinoprotective Effects of Bilberry Anthocyanins via Antioxidant, Anti-Inflammatory, and Anti-Apoptotic Mechanisms in a Visible Light-Induced Retinal Degeneration Model in Pigmented Rabbits. Molecules, [online] 20(12), pp.22395-22410. Available at: https://www.ncbi.nlm.nih.gov/pubmed/26694327.
Larmo, P., Järvinen, R., Setälä, N., Yang, B., Viitanen, M., Engblom, J., Tahvonen, R. and Kallio, H. (2010). Oral Sea Buckthorn Oil Attenuates Tear Film Osmolarity and Symptoms in Individuals with Dry Eye. The Journal of Nutrition, [online] 140(8), pp.1462-1468. Available at: https://www.ncbi.nlm.nih.gov/pubmed/20554904.