Beauty From Within
cyanthox™ MAY Enhance skin regeneration and repair*
Design: Randomized, placebo-controlled, double-blinded, cross-over trial was conducted in 12 human adults.
Serving Size: 500mg Cyanthox™30 per day for 2 hours
Result: Consumption of sea buckthorn proanthocyanidins may lead to an increase in the following stem cells:
Progenitor stem cells
Endothelial stem cells
Mesenchymal stem cells
CyanthOx™ is a unique sea buckthorn extract with a rich combination of Polyphenols, Flavonoids, and Proanthocyanidins, which is one of the strongest plant-based antioxidant.
Conclusion
500mg Cyanthox™30 (150mg sea buckthorn proanthocyanidins) per day stimulate the production of progenitor and mesenchymal stem cells.
Mesenchymal stem cells retain a high degree of plasticity and can contribute regenerative progenitor cells to hematopoietic and non-hematopoietic tissues, including the skin. Therefore, they are important in skin regeneration and repairing.
(Drapeau, Benson and Jensen, 2019) (Fathke, 2004)
CyanthOx™ is a unique sea buckthorn extract with a rich combination of polyphenols, proanthocyanidins, and bioflavonoids, which is one of the strongest plant-based antioxidant.
cyanthox™ MAY promote collagen cross-linking*
Collagen is made of densely packed proteins. Yet, due to internal and external factors like chronic inflammation, the proteins may degrade overtime.
Cyanthox™ may act as a natural and biocompatible collagen cross-linker that helps strengthen the formation of collagen and increase its stability.
(Choi, Kim and Min, 2016)
CyanthOx™ MAy increase SOD, GSH and lower MDA
Design: Randomized, placebo-controlled trial was conducted in 106 human adults aged from 45 - 65 years old.
Materials and Methods: Oral intake of 4 x 0.65g of sea buckthorn capsules (6.5% sea buckthorn proanthocyanidins and 16% Omega 3 (ALA)) or placebo per day for 90 days.
Result: Significant increase in:
SOD by 11%
GSH by 4%
Significant reduction in MDA by 15%.
CyanthOx™ is a unique sea buckthorn extract with a rich combination of polyphenols, proanthocyanidins, and bioflavonoids, which is one of the strongest plant-based antioxidant.
SOD
GSH
MDA
Conclusion: 169mg sea buckthorn proanthocyanidins per day may increase SOD, GSH and lowers MDA.
(Kim et al., 2012)
CyanthOx™ is a unique sea buckthorn extract with a rich combination of polyphenols, proanthocyanidins, and bioflavonoids, which is one of the strongest plant-based antioxidant.
CYANTHOX™ May protect SKIN FROM PHOTOAGING*
Design: Randomized, controlled trial was conducted in 40 mouse weighing from 22g - 25g. The mice were exposed to UVB radiation at 0.17mW/cm² for 20 minutes.
Materials and Methods: Oral intake of 1% sea buckthorn flavonoids extract.
Result:
When compared with the negative control group, the epidermis and its appendages of the treatment group are relatively more complete. The elastic fibers in the dermis layer are less damaged. The collagen fibers are arranged in a more regular pattern.
Control Group
-ve control Group
treatment Group
When compared with negative control group, treatment group was:
19% higher in SOD
55% lower in MDA
37% higher in Collagen
SOD
MDA
Collagen
Conclusion: 1% Sea buckthorn flavonoids may help preserve skin against UVB-induced photoaging via:
Enhancement of SOD and collagen synthesis
Inhibition of increase in MDA and scar hyperplasia
(Xu, 2015)
Omegia® may improve dry skin, loose skin and wrinkle*
Design: Randomized trial was conducted in 60 women of 50 - 70 years old
Dosage: Oral intake of 4 x 500mg sea buckthorn oil and topical application of sea buckthorn cream per day for 3 months
Result: Significant improvement in skin parameters:
Skin hydration was increased by 49%
Skin elasticity was increased by 26%
Wrinkle was reduced by 9%
Organic sea buckthorn complete vegan omega formula for beauty, dry eyes and menopause
Skin Hydration
Skin Elasticity
Wrinkle Reduction
(Yang et al., 2008)
Omeiga® is a unique standardized formula containing Omega-3-6-7-9, beta-carotene, vitamin E, and plant sterols, which are essential for human health.
SEA BUCKTHORN Oil MAY improve atopic dermatitis*
Design: Placebo-controlled, parallel, randomized, double-blind trial was conducted in 49 atopic dermatitis patients
Dosage: Oral intake of 10 x 500mg sea buckthorn fruit oil or seed oil of paraffin oil per day for 4 months
Result:
Symptom severity was rated by SCORAD
0: None
3: Severe
Improvement in atopic eczema symptom
Increase in essential fatty acid in plasma phospholipids and neutral lipids
(Yang et al., 1999)
Reference
Drapeau, C., Benson, K. and Jensen, G. (2019). Rapid and selective mobilization of specific stem cell types after consumption of a polyphenol-rich extract from sea buckthorn berries (Hippophae) in healthy human subjects. Clinical Interventions in Aging, [online] Volume 14, pp.253-263. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368418/.
Fathke, C. (2004). Contribution of Bone Marrow-Derived Cells to Skin: Collagen Deposition and Wound Repair. Stem Cells, [online] 22(5), pp.812-822. Available at: https://www.ncbi.nlm.nih.gov/pubmed/15342945.
Choi, Y., Kim, H. and Min, K. (2016). Effects of proanthocyanidin, a crosslinking agent, on physical and biological properties of collagen hydrogel scaffold. Restorative Dentistry & Endodontics, [online] 41(4), p.296. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107431/.
Zou, Y., Xu, R., Liu, L. and Yang, X. (2010). "Seabuckthorn anthocyanin soft capsule" antioxidant testing for human. The Global Seabuckthorn Research and Development, [online] 8(3), pp.7-10. Available at: http://xueshu.baidu.com/usercenter/paper/show?paperid=474b979300b984490a3869e90e8aa8d7&site=xueshu_se&hitarticle=1.
Xu, M. (2015). The effect of seabuckthorn flavonoids against ultraviolet injury. Chongqing Medicine, [online] 44(33), pp.4618-4620. Available at: http://xueshu.baidu.com/usercenter/paper/show?paperid=b8323f1fac6b81367700a565454bb7ee&site=xueshu_se&hitarticle=1.
Yang, B., Bonfigli, A., Pagani, V., Isohanni, T., von-Knorring, Å., Jutila, A. and Judin, V. (2008). Effects of oral supplementation and topical application of supercritical CO2 extracted sea buckthorn oil on skin ageing of female subjects. Journal of Applied Cosmetology, [online] 27(1), pp.13-25. Available at: https://www.researchgate.net/publication/287943011_Effects_of_oral_supplementation_and_topical_application_of_supercritical_CO2_extracted_sea_buckthorn_oil_on_skin_ageing_of_female_subjects.
Yang, B., 1999. Effects of dietary supplementation with sea buckthorn (Hippophaë rhamnoides) seed and pulp oils on atopic dermatitis. The Journal of Nutritional Biochemistry, [online] 10(11), pp.622-630. Available at: https://pubmed.ncbi.nlm.nih.gov/15539258/.