SEA BUCKTHORN Leaf may relieve constipation*

Design: Randomised, controlled trial was conducted in 100 healthy mice weighing from 17.5 to 19g. The mice were fed with 5mg/kg BW Diphenoxylate to simulate constipation and treated with water for normal and constipated group, 0.7g/kg, 1.4g/kg and 2.1g/kg sea buckthorn leaf tea (SBT) for the treatment groups for 10 days.

Method and Material: Oral intake of 0.7g/kg, 1.4g/kg and 2.1g/kg SBT for the treatment groups for 10 days.

Result: Bowel movement was increased by 40%, intestinal transit time was shorten by 41%, and fecal weight was increased by 33%, when comparing the treatment group with the constipated group.